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206 The gut microbiota further influences neuroendocrine crosstalk due to reduced diversity in the gut microbiota, characterized by reduced abundance of Faecalibacterium prausnitzii, Roseburia, Dialister, Flavonifractor, Alistipes, Haemophilus , and Akkermansia muciniphila , along with an increase in Lactobacillus, Streptococcus, Escherichia, Veillonella , and Collinsella